Postdoctoral position available inStructural variation, Chromatin organization and transcription regulation in Cancers
PI: Chia-Lin Wei, Ph.D.The Jackson Laboratory for Genomic MedicineFarmington, CT
The Wei lab at The Jackson Laboratory's Genomic Medicine campus in the Hartford, CT area is seeking an independent, driven PhD-level scientist (<2 years previous postdoc experience) in genomic technology development, functional (epi)genomics characterization and computational analysis to join our growing research team. Our overarching goal is to understand the chromatin organization and genome structural variation in transcriptional regulation and cancer genome evolution. We employ innovative (epi)genomic profiling and genomic technologies, PDX models, and CRISPR/Cas9 (epi)genome editing platforms to identify key mechanisms driving 3D chromatin conformation and genome rearrangement controlling cancer cell heterogeneity and fitness. The knowledge learned can be used to design new diagnostic and therapeutic targets to contribute cancer monitoring and treatment strategies.
* PhD in genetics, computational biology, molecular/cell biology, or other quantitative science? Knowledge in sequencing technologies, (epi)genomic analysis methods and their applications ? Prior training in analyzing, and interpreting large genomics datasets, examples like epigenome (ATAC-seq, ChIP-seq) and transcriptome (RNA-seq) profiles. Demonstrated proficiency with integrated genomics analyses preferred. Ideal candidates would also have bench skills that would allow them to generate genomics datasets and functionally test hypotheses they generate. ? Prior research experience in the following areas will be preferred: CRISPR/Cas9 (epi)genome editing, microscopy/imaging, mammalian cell culture and microfluidics processing.? Track record of productivity supported by first-author publications in peer-reviewed journals? Outstanding writing and communication skills, with an ability to work both independently and within collaborative teams productively
Candidates will be expected to apply for competitive foundation and federal training fellowships and awards. Exceptional candidates also have the opportunity to become a JAX Postdoctoral Scholar, a selective award that includes an independent research budget, travel funds, and a salary above the standard postdoctoral scale.
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,200 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center, a genomic medicine institute in Farmington, Conn., and facilities in Ellsworth, Maine, Sacramento, Calif., and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX Genomic Medicine is transforming medicine by improving patient care, lowering costs, and increasing life span and health span. JAX Genomic Medicine's research focuses on the complex genetic causes of disease and on the development of genomic solutions tailored to each person's unique genetic makeup.
JAX Genomic Medicine sits on a 17-acre site on the campus of the University of Connecticut Health Center. The 183,500-square-foot facility opened in the fall of 2014. Now, it houses over 300 biomedical researchers, technicians, and support staff in state-of-the-art computing facilities and laboratories.
In Connecticut, JAX resides in the scenic town of Farmington, in the state's capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns. JAX Genomic Medicine is also geographically located within 2 hours of Boston and New York and is close to multiple transportation systems, including bus lines, highways, railroads and international airports.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients' lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 \"Best Places to Work in Academia\" in the United States in a poll conducted by The Scientist magazine!
Our Values:INTEGRITY - Courage and commitment to do what is rightPEOPLE - Inspiring our people to enhance the health of allONE TEAM - Unified by our promise to transform medicine and scienceEXCELLENCE - Achieving world-class resultsINNOVATION - Leading with discovery and creative solutionsSTEWARDSHIP - Caring for and enhancing the resources entrusted to us
What do we have to offer? JAX offers a dynamic and supportive work environment, competitive salaries, and a comprehensive benefits package, including a medical plan, outstanding retirement plan, generous paid time off, and tuition reimbursement including an MBA program. Our campus offers a fitness center with an award-winning wellness program and an onsite full service cafeteria.
Most importantly, every position contributes to JAX's mission of discovering precise genomic solutions for human disease and empowering the global biomedical community in our shared quest to improve human health.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
Associated topics: diagnostic, disease, disorder, genetic, instructor md, mental, oncology, otolaryngology, pathophysiology, public health
* The salary listed in the header is an estimate based on salary data for similar jobs in the same area. Salary or compensation data found in the job description is accurate.